Chitosan Nanocapsules for Treating Psoriasis

Image from Microscopy Electronic Transition of a chitosan nanocapsule. Image obtained from Advancel web site

Advancell and the dermatological company Isdin have shown in clinical trials of phase I / II the efficacy of Dermosome Technology ® for topical treatment of psoriasis with a formulation of cyclosporine.

The Dermosome Technology ® is made up of chitosan nanocapsules for topical administration of active ingredients. These nanocapsules are formed by an oily core, which houses the active ingredient, which is coated with chitosan.

The technology adheres to the skin, allowing a longer time of contact, combined with its tiny size, increases the contact area between skin and structure, causing the active to accumulate significantly at the level of the epidermis.

Later this year, Advancell Nanosystems will have 2 or 3 new projects using Dermosome ® Technology to other skin diseases other than psoriasis.

Advancell was founded in 2001 as a result of the merger between CellTec (spin-off of the department of cell biology at the University of Barcelona) and Xenotest (spin-off from the experimental hepatology unit of the Hospital Universitario La Fe of Valencia)